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Inhibition of Nuclear Receptor Binding SET Domain 2/Multiple Myeloma SET Domain by LEM-06 Implication for Epigenetic Cancer Therapies
BACKGROUND: Multiple myeloma SET domain (MMSET)/nuclear receptor binding SET domain 2 (NSD2) is a lysine histone methyltransferase (HMTase) and bona fide oncoprotein found aberrantly expressed in several cancers, suggesting potential role for novel therapeutic strategies. In particular, MMSET/NSD2 i...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society of Cancer Prevention
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492355/ https://www.ncbi.nlm.nih.gov/pubmed/26151044 http://dx.doi.org/10.15430/JCP.2015.20.2.113 |