Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) system is an adaptive immune system in bacteria and archaea that has recently been exploited for genome engineering. Mutant mice can be generated in one step through direct delivery of the CRISPR/Ca...

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Detalles Bibliográficos
Autores principales: Qin, Wenning, Dion, Stephanie L., Kutny, Peter M., Zhang, Yingfan, Cheng, Albert W., Jillette, Nathaniel L., Malhotra, Ankit, Geurts, Aron M., Chen, Yi-Guang, Wang, Haoyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492369/
https://www.ncbi.nlm.nih.gov/pubmed/25819794
http://dx.doi.org/10.1534/genetics.115.176594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492369/
https://www.ncbi.nlm.nih.gov/pubmed/25819794
http://dx.doi.org/10.1534/genetics.115.176594

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