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FGF8, c-Abl and p300 participate in a pathway that controls stability and function of the ΔNp63α protein

The p63 transcription factor, homolog to the p53 tumor suppressor gene, plays a crucial role in epidermal and limb development, as its mutations are associated to human congenital syndromes characterized by skin, craniofacial and limb defects. While limb and skin-specific p63 transcriptional targets...

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Detalles Bibliográficos
Autores principales: Restelli, Michela, Molinari, Elisa, Marinari, Barbara, Conte, Daniele, Gnesutta, Nerina, Costanzo, Antonio, Merlo, Giorgio Roberto, Guerrini, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492388/
https://www.ncbi.nlm.nih.gov/pubmed/25911675
http://dx.doi.org/10.1093/hmg/ddv151