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FGF8, c-Abl and p300 participate in a pathway that controls stability and function of the ΔNp63α protein
The p63 transcription factor, homolog to the p53 tumor suppressor gene, plays a crucial role in epidermal and limb development, as its mutations are associated to human congenital syndromes characterized by skin, craniofacial and limb defects. While limb and skin-specific p63 transcriptional targets...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492388/ https://www.ncbi.nlm.nih.gov/pubmed/25911675 http://dx.doi.org/10.1093/hmg/ddv151 |