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Assorted Processing of Synthetic Trans-Acting siRNAs and Its Activity in Antiviral Resistance

The use of syn-tasiRNAs has been proposed as an RNA interference technique alternative to those previously described: hairpin based, virus induced gene silencing or artificial miRNAs. In this study we engineered the TAS1c locus to impair Plum pox virus (PPV) infection by replacing the five native si...

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Detalles Bibliográficos
Autores principales: Zhao, Mingmin, San León, David, Mesel, Frida, García, Juan Antonio, Simón-Mateo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492489/
https://www.ncbi.nlm.nih.gov/pubmed/26147769
http://dx.doi.org/10.1371/journal.pone.0132281