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Ubiquitous Over-Expression of Chromatin Remodeling Factor SRG3 Ameliorates the T Cell-Mediated Exacerbation of EAE by Modulating the Phenotypes of both Dendritic Cells and Macrophages

Although SWI3-related gene (SRG3), a chromatin remodeling factor, is critical for various biological processes including early embryogenesis and thymocyte development, it is unclear whether SRG3 is involved in the differentiation of CD4(+) T cells, the key mediator of adaptive immune responses. Beca...

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Detalles Bibliográficos
Autores principales: Lee, Sung Won, Park, Hyun Jung, Jeon, Sung Ho, Lee, Changjin, Seong, Rho Hyun, Park, Se-Ho, Hong, Seokmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492541/
https://www.ncbi.nlm.nih.gov/pubmed/26147219
http://dx.doi.org/10.1371/journal.pone.0132329