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Systematic Comparison and Validation of Quantitative Real-Time PCR Methods for the Quantitation of Adeno-Associated Viral Products

Adeno-associated viral (AAV) vectors show great promise for gene therapy because of their excellent safety profile; however, development of robust dose-determining assays for AAV has presented a significant challenge. With the ultimate goal of future harmonization and standardization of AAV dose det...

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Detalles Bibliográficos
Autores principales: Werling, Natalie Jayne, Satkunanathan, Stifani, Thorpe, Robin, Zhao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492554/
https://www.ncbi.nlm.nih.gov/pubmed/25953194
http://dx.doi.org/10.1089/hgtb.2015.013