Cargando…

Dendritic Versus Tumor Cell Presentation of Autologous Tumor Antigens for Active Specific Immunotherapy in Metastatic Melanoma: Impact on Long-Term Survival by Extent of Disease at the Time of Treatment

In patients with metastatic melanoma, sequential single-arm and randomized phase II trials with a therapeutic vaccine consisting of autologous dendritic cells (DCs) loaded with antigens from self-renewing, proliferating, irradiated autologous tumor cells (DC-TC) showed superior survival compared wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Dillman, Robert O., McClay, Edward F., Barth, Neil M., Amatruda, Thomas T., Schwartzberg, Lee S., Mahdavi, Khosrow, de Leon, Cristina, Ellis, Robin E., DePriest, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492594/
https://www.ncbi.nlm.nih.gov/pubmed/26083950
http://dx.doi.org/10.1089/cbr.2015.1843