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Dendritic Versus Tumor Cell Presentation of Autologous Tumor Antigens for Active Specific Immunotherapy in Metastatic Melanoma: Impact on Long-Term Survival by Extent of Disease at the Time of Treatment
In patients with metastatic melanoma, sequential single-arm and randomized phase II trials with a therapeutic vaccine consisting of autologous dendritic cells (DCs) loaded with antigens from self-renewing, proliferating, irradiated autologous tumor cells (DC-TC) showed superior survival compared wit...
Autores principales: | Dillman, Robert O., McClay, Edward F., Barth, Neil M., Amatruda, Thomas T., Schwartzberg, Lee S., Mahdavi, Khosrow, de Leon, Cristina, Ellis, Robin E., DePriest, Carol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492594/ https://www.ncbi.nlm.nih.gov/pubmed/26083950 http://dx.doi.org/10.1089/cbr.2015.1843 |
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