Cargando…

Production of Cloned Miniature Pigs Expressing High Levels of Human Apolipoprotein(a) in Plasma

High lipoprotein(a) [Lp(a)] levels are a major risk factor for the development of atherosclerosis. However, because apolipoprotein(a) [apo(a)], the unique component of Lp(a), is found only in primates and humans, the study of human Lp(a) has been hampered due to the lack of appropriate animal models...

Descripción completa

Detalles Bibliográficos
Autores principales: Ozawa, Masayuki, Himaki, Takehiro, Ookutsu, Shoji, Mizobe, Yamato, Ogawa, Junki, Miyoshi, Kazuchika, Yabuki, Akira, Fan, Jianglin, Yoshida, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492603/
https://www.ncbi.nlm.nih.gov/pubmed/26147378
http://dx.doi.org/10.1371/journal.pone.0132155