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Production of Cloned Miniature Pigs Expressing High Levels of Human Apolipoprotein(a) in Plasma

High lipoprotein(a) [Lp(a)] levels are a major risk factor for the development of atherosclerosis. However, because apolipoprotein(a) [apo(a)], the unique component of Lp(a), is found only in primates and humans, the study of human Lp(a) has been hampered due to the lack of appropriate animal models...

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Detalles Bibliográficos
Autores principales: Ozawa, Masayuki, Himaki, Takehiro, Ookutsu, Shoji, Mizobe, Yamato, Ogawa, Junki, Miyoshi, Kazuchika, Yabuki, Akira, Fan, Jianglin, Yoshida, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492603/
https://www.ncbi.nlm.nih.gov/pubmed/26147378
http://dx.doi.org/10.1371/journal.pone.0132155

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