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Protective Effects of N-Acetyl Cysteine against Diesel Exhaust Particles-Induced Intracellular ROS Generates Pro-Inflammatory Cytokines to Mediate the Vascular Permeability of Capillary-Like Endothelial Tubes

Exposure to diesel exhaust particles (DEP) is associated with pulmonary and cardiovascular diseases. Previous studies using in vitro endothelial tubes as a simplified model of capillaries have found that DEP-induced ROS increase vascular permeability with rearrangement or internalization of adherens...

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Detalles Bibliográficos
Autores principales: Tseng, Chia-Yi, Chang, Jing-Fen, Wang, Jhih-Syuan, Chang, Yu-Jung, Gordon, Marion K., Chao, Ming-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492618/
https://www.ncbi.nlm.nih.gov/pubmed/26148005
http://dx.doi.org/10.1371/journal.pone.0131911