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Synergistic Induction of Potential Warburg Effect in Zebrafish Hepatocellular Carcinoma by Co-Transgenic Expression of Myc and xmrk Oncogenes

Previously we have generated inducible liver tumor models by transgenic expression of Myc or xmrk (activated EGFR homolog) oncogenes in zebrafish. To investigate the interaction of the two oncogenes, we crossed the two transgenic lines and observed more severe and faster hepatocarcinogenesis in Myc/...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Zheng, Weiling, Li, Hankun, Li, Caixia, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492623/
https://www.ncbi.nlm.nih.gov/pubmed/26147004
http://dx.doi.org/10.1371/journal.pone.0132319