Discovery of 3-n-butyl-2,3-dihydro-1H-isoindol-1-one as a potential anti-ischemic stroke agent

To develop novel anti-ischemic stroke agents with better therapeutic efficacy and bioavailability, we designed and synthesized a series of 3-alkyl-2,3-dihydro-1H-isoindol-1-ones compounds (3a–i) derivatives, one of which (3d) exhibited the strongest inhibitory activity for the adenosine diphosphate-...

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Detalles Bibliográficos
Autores principales: Lan, Zujian, Xu, Xiaoyu, Xu, Wenkai, Li, Jin, Liang, Zengrong, Zhang, Xuefei, Lei, Ming, Zhao, Chunshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492651/
https://www.ncbi.nlm.nih.gov/pubmed/26170623
http://dx.doi.org/10.2147/DDDT.S84731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492651/
https://www.ncbi.nlm.nih.gov/pubmed/26170623
http://dx.doi.org/10.2147/DDDT.S84731

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