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NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain

The development of nitric oxide (NO)- and hydrogen sulfide (H(2)S)-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) has generated more potent anti-inflammatory drugs with increased safety profiles. A new hybrid molecule incorporating both NO and H(2)S donors into aspirin (NOSH-aspirin) was re...

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Detalles Bibliográficos
Autores principales: Fonseca, Miriam D, Cunha, Fernando Q, Kashfi, Khosrow, Cunha, Thiago M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492749/
https://www.ncbi.nlm.nih.gov/pubmed/26236481
http://dx.doi.org/10.1002/prp2.133