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Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition

T cells are crucial players in cell-mediated immunity. The specificity of their receptor, the T cell receptor (TCR), is central for the immune system to distinguish foreign from host antigens. Superantigens are bacterial toxins capable of inducing a toxic immune response by cross-linking the TCR and...

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Detalles Bibliográficos
Autores principales: Rödström, Karin E. J., Regenthal, Paulina, Lindkvist-Petersson, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492778/
https://www.ncbi.nlm.nih.gov/pubmed/26147596
http://dx.doi.org/10.1371/journal.pone.0131988