Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Staphylococcus aureus Infections

Calprotectin, the most abundant cytoplasmic protein in neutrophils, suppresses the growth of Staphylococcus aureus by sequestering the nutrient metal ions Zn and Mn. Here we show that calprotectin can also enhance the activity of the SaeRS two component system (TCS), a signaling system essential for...

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Detalles Bibliográficos
Autores principales: Cho, Hoonsik, Jeong, Do-Won, Liu, Qian, Yeo, Won-Sik, Vogl, Thomas, Skaar, Eric P., Chazin, Walter J., Bae, Taeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492782/
https://www.ncbi.nlm.nih.gov/pubmed/26147796
http://dx.doi.org/10.1371/journal.ppat.1005026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492782/
https://www.ncbi.nlm.nih.gov/pubmed/26147796
http://dx.doi.org/10.1371/journal.ppat.1005026

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