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Tocilizumab unmasks a stage-dependent interleukin-6 component in statin-induced apoptosis of metastatic melanoma cells

The interleukin (IL)-6 inhibits the growth of early-stage melanoma cells, but not metastatic cells. Metastatic melanoma cells are susceptible to statin-induced apoptosis, but this is not clear for early-stage melanoma cells. This study aimed to investigate the IL-6 susceptibility of melanoma cells f...

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Detalles Bibliográficos
Autores principales: Minichsdorfer, Christoph, Wasinger, Christine, Sieczkowski, Evelyn, Atil, Bihter, Hohenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492793/
https://www.ncbi.nlm.nih.gov/pubmed/26020489
http://dx.doi.org/10.1097/CMR.0000000000000172