A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease in adults. Numerous studies indicate that ALS is a systemic disease that affects whole body physiology and metabolic homeostasis. Using a mouse model of the disease (SOD1(G86R)), we investigated muscle physiology and m...

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Detalles Bibliográficos
Autores principales: Palamiuc, Lavinia, Schlagowski, Anna, Ngo, Shyuan T, Vernay, Aurelia, Dirrig-Grosch, Sylvie, Henriques, Alexandre, Boutillier, Anne-Laurence, Zoll, Joffrey, Echaniz-Laguna, Andoni, Loeffler, Jean-Philippe, René, Frédérique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492815/
https://www.ncbi.nlm.nih.gov/pubmed/25820275
http://dx.doi.org/10.15252/emmm.201404433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492815/
https://www.ncbi.nlm.nih.gov/pubmed/25820275
http://dx.doi.org/10.15252/emmm.201404433

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