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Consequence of the tumor-associated conversion to cyclin D1b

Clinical evidence suggests that cyclin D1b, a variant of cyclin D1, is associated with tumor progression and poor outcome. However, the underlying molecular basis was unknown. Here, novel models were created to generate a genetic switch from cyclin D1 to cyclin D1b. Extensive analyses uncovered over...

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Detalles Bibliográficos
Autores principales: Augello, Michael A, Berman-Booty, Lisa D, Carr, Richard, Yoshida, Akihiro, Dean, Jeffry L, Schiewer, Matthew J, Feng, Felix Y, Tomlins, Scott A, Gao, Erhe, Koch, Walter J, Benovic, Jeffrey L, Diehl, John Alan, Knudsen, Karen E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492821/
https://www.ncbi.nlm.nih.gov/pubmed/25787974
http://dx.doi.org/10.15252/emmm.201404242