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Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo
Epidermal growth factor receptor (EGFR) inhibitors have demonstrated efficacy in squamous cell carcinoma of the head and neck (SCCHN). In addition to EGFR, other ErbB family members are expressed and activated in SCCHN. Afatinib is an ErbB family blocker that has been approved for treating patients...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492891/ https://www.ncbi.nlm.nih.gov/pubmed/25559287 http://dx.doi.org/10.1007/s11523-014-0353-6 |