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Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder

Schizophrenia is associated with alterations in working memory that reflect dysfunction of dorsolateral prefrontal cortex (DLPFC) circuitry. Working memory depends on the activity of excitatory pyramidal cells in DLPFC layer 3, and to a lesser extent in layer 5. Although many studies have profiled g...

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Detalles Bibliográficos
Autores principales: Arion, Dominique, Corradi, John P., Tang, Shaowu, Datta, Dibyadeep, Boothe, Franklyn, He, Aiqing, Cacace, Angela M., Zaczek, Robert, Albright, Charles F., Tseng, George, Lewis, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492919/
https://www.ncbi.nlm.nih.gov/pubmed/25560755
http://dx.doi.org/10.1038/mp.2014.171