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In an Ovine Model of Polycystic Ovary Syndrome (PCOS) Prenatal Androgens Suppress Female Fetal Renal Gluconeogenesis

Increased maternal androgen exposure during pregnancy programmes a polycystic ovary syndrome (PCOS)-like condition, with metabolic dysfunction, in adult female offspring. Other in utero exposures associated with the development of insulin resistance, such as intrauterine growth restriction and expos...

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Detalles Bibliográficos
Autores principales: Connolly, Fiona, Rae, Michael T., Späth, Katharina, Boswell, Lyndsey, McNeilly, Alan S., Duncan, W. Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492923/
https://www.ncbi.nlm.nih.gov/pubmed/26148093
http://dx.doi.org/10.1371/journal.pone.0132113