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Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice

Disruptions in circadian rhythms and dopaminergic activity are involved in the pathophysiology of bipolar disorder, though their interaction remains unclear. Moreover, a lack of animal models that display spontaneous cycling between mood states has hindered our mechanistic understanding of mood swit...

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Detalles Bibliográficos
Autores principales: Sidor, Michelle M., Spencer, Sade M., Dzirasa, Kafui, Parekh, Puja K., Tye, Kay M., Warden, Melissa R., Arey, Rachel N., Enwright, John F, Jacobsen, Jacob PR, Kumar, Sunil, Remillard, Erin M, Caron, Marc G., Deisseroth, Karl, McClung, Colleen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492925/
https://www.ncbi.nlm.nih.gov/pubmed/25560763
http://dx.doi.org/10.1038/mp.2014.167