Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

INTRODUCTION: Toll-like receptors (TLRs) play an important role in the recognition of microbial products and in host defense against infection. However, the massive release of inflammatory mediators into the bloodstream following TLR activation following sepsis is thought to contribute to disease pa...

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Detalles Bibliográficos
Autores principales: Lima, Cristiano Xavier, Souza, Danielle Gloria, Amaral, Flavio Almeida, Fagundes, Caio Tavares, Rodrigues, Irla Paula Stopa, Alves-Filho, Jose Carlos, Kosco-Vilbois, Marie, Ferlin, Walter, Shang, Limin, Elson, Greg, Teixeira, Mauro Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492955/
https://www.ncbi.nlm.nih.gov/pubmed/26147469
http://dx.doi.org/10.1371/journal.pone.0132336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492955/
https://www.ncbi.nlm.nih.gov/pubmed/26147469
http://dx.doi.org/10.1371/journal.pone.0132336

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