Cargando…

Microprocessor mediates transcriptional termination in long noncoding microRNA genes

MicroRNA (miRNA) play a major role in the post-transcriptional regulation of gene expression. Mammalian miRNA biogenesis begins with co-transcriptional cleavage of RNA polymerase II (Pol II) transcripts by the Microprocessor complex. While most miRNA are located within introns of protein coding gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Dhir, Ashish, Dhir, Somdutta, Proudfoot, Nick J., Jopling, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492989/
https://www.ncbi.nlm.nih.gov/pubmed/25730776
http://dx.doi.org/10.1038/nsmb.2982