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Microprocessor mediates transcriptional termination in long noncoding microRNA genes
MicroRNA (miRNA) play a major role in the post-transcriptional regulation of gene expression. Mammalian miRNA biogenesis begins with co-transcriptional cleavage of RNA polymerase II (Pol II) transcripts by the Microprocessor complex. While most miRNA are located within introns of protein coding gene...
Autores principales: | Dhir, Ashish, Dhir, Somdutta, Proudfoot, Nick J., Jopling, Catherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492989/ https://www.ncbi.nlm.nih.gov/pubmed/25730776 http://dx.doi.org/10.1038/nsmb.2982 |
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