Identification of an Immunogenic Mimic of a Conserved Epitope on the Plasmodium falciparum Blood Stage Antigen AMA1 Using Virus-Like Particle (VLP) Peptide Display

We have developed a peptide display platform based on VLPs of the RNA bacteriophage MS2 that combines the high immunogenicity of VLP display with affinity selection capabilities. Random peptides can be displayed on the VLP surface by genetically inserting sequences into a surface-exposed loop of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Crossey, Erin, Frietze, Kathryn, Narum, David L., Peabody, David S., Chackerian, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493041/
https://www.ncbi.nlm.nih.gov/pubmed/26147502
http://dx.doi.org/10.1371/journal.pone.0132560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493041/
https://www.ncbi.nlm.nih.gov/pubmed/26147502
http://dx.doi.org/10.1371/journal.pone.0132560

Ejemplares similares