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Glypican Is a Modulator of Netrin-Mediated Axon Guidance

Netrin is a key axon guidance cue that orients axon growth during neural circuit formation. However, the mechanisms regulating netrin and its receptors in the extracellular milieu are largely unknown. Here we demonstrate that in Caenorhabditis elegans, LON-2/glypican, a heparan sulfate proteoglycan,...

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Detalles Bibliográficos
Autores principales: Blanchette, Cassandra R., Perrat, Paola N., Thackeray, Andrea, Bénard, Claire Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493048/
https://www.ncbi.nlm.nih.gov/pubmed/26148345
http://dx.doi.org/10.1371/journal.pbio.1002183