Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells

Chemotherapy resistance is the major reason for the failure of ovarian cancer treatment. One mechanism behind chemo-resistance involves the upregulation of multidrug resistance (MDR) genes (ABC transporters) that effectively transport (efflux) drugs out of the tumor cells. As a common symptom in sta...

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Detalles Bibliográficos
Autores principales: Mo, Lihong, Pospichalova, Vendula, Huang, Zhiqing, Murphy, Susan K., Payne, Sturgis, Wang, Fang, Kennedy, Margaret, Cianciolo, George J., Bryja, Vitezslav, Pizzo, Salvatore V., Bachelder, Robin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493087/
https://www.ncbi.nlm.nih.gov/pubmed/26148191
http://dx.doi.org/10.1371/journal.pone.0131579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493087/
https://www.ncbi.nlm.nih.gov/pubmed/26148191
http://dx.doi.org/10.1371/journal.pone.0131579

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