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Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay
The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to investigate the following issues: transactivation specificity of NF-κB proteins acting as homodimers o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493129/ https://www.ncbi.nlm.nih.gov/pubmed/26147604 http://dx.doi.org/10.1371/journal.pone.0130170 |