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Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay

The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to investigate the following issues: transactivation specificity of NF-κB proteins acting as homodimers o...

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Detalles Bibliográficos
Autores principales: Sharma, Vasundhara, Jordan, Jennifer J., Ciribilli, Yari, Resnick, Michael A., Bisio, Alessandra, Inga, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493129/
https://www.ncbi.nlm.nih.gov/pubmed/26147604
http://dx.doi.org/10.1371/journal.pone.0130170

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