In Silico Identification and In Vitro and In Vivo Validation of Anti-Psychotic Drug Fluspirilene as a Potential CDK2 Inhibitor and a Candidate Anti-Cancer Drug

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Surgical resection and conventional chemotherapy and radiotherapy ultimately fail due to tumor recurrence and HCC’s resistance. The development of novel therapies against HCC is thus urgently required. Th...

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Detalles Bibliográficos
Autores principales: Shi, Xi-Nan, Li, Hongjian, Yao, Hong, Liu, Xu, Li, Ling, Leung, Kwong-Sak, Kung, Hsiang-fu, Lu, Di, Wong, Man-Hon, Lin, Marie Chia-mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493148/
https://www.ncbi.nlm.nih.gov/pubmed/26147897
http://dx.doi.org/10.1371/journal.pone.0132072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493148/
https://www.ncbi.nlm.nih.gov/pubmed/26147897
http://dx.doi.org/10.1371/journal.pone.0132072

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