Metabolic reprogramming in macrophages and dendritic cells in innate immunity

Activation of macrophages and dendritic cells (DCs) by pro-inflammatory stimuli causes them to undergo a metabolic switch towards glycolysis and away from oxidative phosphorylation (OXPHOS), similar to the Warburg effect in tumors. However, it is only recently that the mechanisms responsible for thi...

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Detalles Bibliográficos
Autores principales: Kelly, Beth, O'Neill, Luke AJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493277/
https://www.ncbi.nlm.nih.gov/pubmed/26045163
http://dx.doi.org/10.1038/cr.2015.68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493277/
https://www.ncbi.nlm.nih.gov/pubmed/26045163
http://dx.doi.org/10.1038/cr.2015.68

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