Cargando…
Metabolic reprogramming in macrophages and dendritic cells in innate immunity
Activation of macrophages and dendritic cells (DCs) by pro-inflammatory stimuli causes them to undergo a metabolic switch towards glycolysis and away from oxidative phosphorylation (OXPHOS), similar to the Warburg effect in tumors. However, it is only recently that the mechanisms responsible for thi...
Autores principales: | Kelly, Beth, O'Neill, Luke AJ |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493277/ https://www.ncbi.nlm.nih.gov/pubmed/26045163 http://dx.doi.org/10.1038/cr.2015.68 |
Ejemplares similares
-
Immunometabolism governs dendritic cell and macrophage function
por: O’Neill, Luke A.J., et al.
Publicado: (2016) -
Metabolic Reprograming in Macrophage Polarization
por: Galván-Peña, Silvia, et al.
Publicado: (2014) -
A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation
por: Williams, Niamh C., et al.
Publicado: (2018) -
Dendritic cells as immune regulators: the mouse model
por: Griffiths, KL, et al.
Publicado: (2008) -
Rocking the world of innate immunity: an interview with Luke O'Neill
por: O'Neill, Luke A. J.
Publicado: (2018)