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Tissue Transglutaminase-Regulated Transformed Growth Factor-β1 in the Parasite Links Schistosoma japonicum Infection with Liver Fibrosis

Transforming growth factor (TGF-β1) is among the strongest factors of liver fibrogenesis, but its association with Schistosoma-caused liver fibrosis is controversial. Tissue transglutaminase (tTG) is the principal enzyme controlling TGF-β1 maturation and contributes to Sj-infected liver fibrosis. He...

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Detalles Bibliográficos
Autores principales: Tang, Juanjuan, Zhu, Xunmin, Zhao, Jingjing, Fung, Mingchiu, Li, Yinyan, Gao, Zhiyan, Yan, Suikai, Li, Xiaomin, Ji, Xiaofang, Su, Fang, Li, Zi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493306/
https://www.ncbi.nlm.nih.gov/pubmed/26199461
http://dx.doi.org/10.1155/2015/659378