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A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes

Following partial hepatectomy, a coordinated series of molecular events occurs to regulate hepatocyte entry into the cell cycle to recover lost mass. In rats during the first 6 h following resection, hepatocytes are primed by a tightly controlled cytokine response to prepare hepatocytes to begin rep...

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Detalles Bibliográficos
Autores principales: Cook, Daniel J., Patra, Biswanath, Kuttippurathu, Lakshmi, Hoek, Jan B., Vadigepalli, Rajanikanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493398/
https://www.ncbi.nlm.nih.gov/pubmed/26217230
http://dx.doi.org/10.3389/fphys.2015.00189