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A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes
Following partial hepatectomy, a coordinated series of molecular events occurs to regulate hepatocyte entry into the cell cycle to recover lost mass. In rats during the first 6 h following resection, hepatocytes are primed by a tightly controlled cytokine response to prepare hepatocytes to begin rep...
Autores principales: | Cook, Daniel J., Patra, Biswanath, Kuttippurathu, Lakshmi, Hoek, Jan B., Vadigepalli, Rajanikanth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493398/ https://www.ncbi.nlm.nih.gov/pubmed/26217230 http://dx.doi.org/10.3389/fphys.2015.00189 |
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