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CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages

Pulmonary metastasis of breast cancer cells is promoted by a distinct population of macrophages, metastasis-associated macrophages (MAMs), which originate from inflammatory monocytes (IMs) recruited by the CC-chemokine ligand 2 (CCL2). We demonstrate here that, through activation of the CCL2 recepto...

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Detalles Bibliográficos
Autores principales: Kitamura, Takanori, Qian, Bin-Zhi, Soong, Daniel, Cassetta, Luca, Noy, Roy, Sugano, Gaël, Kato, Yu, Li, Jiufeng, Pollard, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493415/
https://www.ncbi.nlm.nih.gov/pubmed/26056232
http://dx.doi.org/10.1084/jem.20141836