Increasing the Biological Stability Profile of a New Chemical Entity, UPEI-104, and Potential Use as a Neuroprotectant Against Reperfusion-Injury

Previous work in our laboratory demonstrated the utility of synthetic combinations of two naturally occurring, biologically active compounds. In particular, we combined two known anti-oxidant compounds, lipoic acid and apocynin, covalently linked via an ester bond (named UPEI-100). In an animal mode...

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Detalles Bibliográficos
Autores principales: Saleh, Tarek M., Connell, Barry J., Kucukkaya, Inan, Abd-El-Aziz, Alaa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493460/
https://www.ncbi.nlm.nih.gov/pubmed/25906324
http://dx.doi.org/10.3390/brainsci5020130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493460/
https://www.ncbi.nlm.nih.gov/pubmed/25906324
http://dx.doi.org/10.3390/brainsci5020130

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