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The Hypothermic Influence on CHOP and Ero1-α in an Endoplasmic Reticulum Stress Model of Cerebral Ischemia

Hypoxia induced endoplasmic reticulum stress causes accumulation of unfolded proteins in the endoplasmic reticulum and activates the unfolded protein response, resulting in apoptosis through CCAAT-enhancer-binding protein homologous protein (CHOP) activation. In an in vitro and in vivo model of isch...

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Detalles Bibliográficos
Autores principales: Poone, Gagandip K., Hasseldam, Henrik, Munkholm, Nina, Rasmussen, Rune S., Grønberg, Nina V., Johansen, Flemming F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493463/
https://www.ncbi.nlm.nih.gov/pubmed/25989620
http://dx.doi.org/10.3390/brainsci5020178