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Carbohydrate-Derived Amphiphilic Macromolecules: A Biophysical Structural Characterization and Analysis of Binding Behaviors to Model Membranes

The design and synthesis of enhanced membrane-intercalating biomaterials for drug delivery or vascular membrane targeting is currently challenged by the lack of screening and prediction tools. The present work demonstrates the generation of a Quantitative Structural Activity Relationship model (QSAR...

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Detalles Bibliográficos
Autores principales: Martin, Adriana A. T., Tomasini, Michael, Kholodovych, Vladyslav, Gu, Li, Sommerfeld, Sven Daniel, Uhrich, Kathryn E., Murthy, N. Sanjeeva, Welsh, William J., Moghe, Prabhas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493506/
https://www.ncbi.nlm.nih.gov/pubmed/25855953
http://dx.doi.org/10.3390/jfb6020171