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Human Keratoconus Cell Contractility is Mediated by Transforming Growth Factor-Beta Isoforms

Keratoconus (KC) is a progressive disease linked to defects in the structural components of the corneal stroma. The extracellular matrix (ECM) is secreted and assembled by corneal keratocytes and regulated by transforming growth factor-β (TGF-β). We have previously identified alterations in the TGF-...

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Detalles Bibliográficos
Autores principales: Lyon, Desiree’, McKay, Tina B., Sarkar-Nag, Akhee, Priyadarsini, Shrestha, Karamichos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493522/
https://www.ncbi.nlm.nih.gov/pubmed/26096146
http://dx.doi.org/10.3390/jfb6020422