Mechanistic studies of a novel C-S lyase in ergothioneine biosynthesis: the involvement of a sulfenic acid intermediate

Ergothioneine is a histidine thio-derivative isolated in 1909. In ergothioneine biosynthesis, the combination of a mononuclear non-heme iron enzyme catalyzed oxidative C-S bond formation reaction and a PLP-mediated C-S lyase (EgtE) reaction results in a net sulfur transfer from cysteine to histidine...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Heng, Hu, Wen, Naowarojna, Nathchar, Her, Ampon Sae, Wang, Shu, Desai, Rushil, Qin, Li, Chen, Xiaoping, Liu, Pinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493562/
https://www.ncbi.nlm.nih.gov/pubmed/26149121
http://dx.doi.org/10.1038/srep11870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493562/
https://www.ncbi.nlm.nih.gov/pubmed/26149121
http://dx.doi.org/10.1038/srep11870

Ejemplares similares