Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities

This study aimed to explore the effect and mechanisms of rhein on sepsis-induced acute kidney injury by injecting lipopolysaccharide (LPS) and cecal ligation and puncture (CLP) in vivo, and on LPS-induced HK-2 cells in vitro. For histopathological analysis, rhein effectively attenuated the severity...

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Detalles Bibliográficos
Autores principales: Yu, Chen, Qi, Dong, Sun, Ju-Feng, Li, Peng, Fan, Hua-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493574/
https://www.ncbi.nlm.nih.gov/pubmed/26149595
http://dx.doi.org/10.1038/srep11822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493574/
https://www.ncbi.nlm.nih.gov/pubmed/26149595
http://dx.doi.org/10.1038/srep11822

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