Cargando…

Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities

This study aimed to explore the effect and mechanisms of rhein on sepsis-induced acute kidney injury by injecting lipopolysaccharide (LPS) and cecal ligation and puncture (CLP) in vivo, and on LPS-induced HK-2 cells in vitro. For histopathological analysis, rhein effectively attenuated the severity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Chen, Qi, Dong, Sun, Ju-Feng, Li, Peng, Fan, Hua-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493574/ https://www.ncbi.nlm.nih.gov/pubmed/26149595 http://dx.doi.org/10.1038/srep11822

Ejemplares similares

Paeonol protects endotoxin-induced acute kidney injury: potential mechanism of inhibiting TLR4-NF-κB signal pathway
por: Fan, Hua-Ying, et al.
Publicado: (2016)

Rhein attenuates inflammation through inhibition of NF-κB and NALP3 inflammasome in vivo and in vitro
por: Ge, Hui, et al.
Publicado: (2017)

Rhein inhibits malignant phenotypes of human renal cell carcinoma by impacting on MAPK/NF-κB signaling pathways
por: Ma, Ya-Li, et al.
Publicado: (2018)

Rhein Inhibits NF-κB Signaling Pathway to Alleviate Inflammatory Response and Oxidative Stress of Rats with Chronic Glomerulonephritis
por: Chen, Qian, et al.
Publicado: (2022)

Propofol protects against endotoxin-induced myocardial injury by inhibiting NF-κB-mediated inflammation
por: Yang, Zhijun, et al.
Publicado: (2018)

Retracted: Rhein Inhibits NF-κB Signaling Pathway to Alleviate Inflammatory Response and Oxidative Stress of Rats with Chronic Glomerulonephritis
por: and Biomechanics, Applied Bionics
Publicado: (2023)

Osthole protects sepsis-induced acute kidney injury via down-regulating NF-κB signal pathway
por: Yu, Chen, et al.
Publicado: (2016)

NFκB and Kidney Injury
por: Song, Ning, et al.
Publicado: (2019)

Rhein Suppresses Lung Inflammatory Injury Induced by Human Respiratory Syncytial Virus Through Inhibiting NLRP3 Inflammasome Activation via NF-κB Pathway in Mice
por: Shen, Cunsi, et al.
Publicado: (2020)

Mesenchymal Stem Cell-Conditioned Medium Induces Neutrophil Apoptosis Associated with Inhibition of the NF-κB Pathway in Endotoxin-Induced Acute Lung Injury
por: Su, Vincent Yi-Fong, et al.
Publicado: (2019)

Neferine Attenuates Acute Kidney Injury by Inhibiting NF-κB Signaling and Upregulating Klotho Expression
por: Li, Huihui, et al.
Publicado: (2019)

Anti-influenza A virus activity of rhein through regulating oxidative stress, TLR4, Akt, MAPK, and NF-κB signal pathways
por: Wang, Qian-Wen, et al.
Publicado: (2018)

Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF-κB Signaling Pathway
por: Zhao, Hongyu, et al.
Publicado: (2016)

Rhein Meeting Program
por: The HiLumi LHC Collaboration
Publicado: (2014)

Anti-Inflammatory Effects of Shenfu Injection against Acute Lung Injury through Inhibiting HMGB1-NF-κB Pathway in a Rat Model of Endotoxin Shock
por: Liu, Xia, et al.
Publicado: (2019)

The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury
por: Choi, Won-Il, et al.
Publicado: (2009)

Hispidulin Ameliorates Endotoxin-Induced Acute Kidney Injury in Mice
por: Kim, Kiryeong, et al.
Publicado: (2022)

Combination therapy of Ulinastatin with Thrombomodulin alleviates endotoxin (LPS) - induced liver and kidney injury via inhibiting apoptosis, oxidative stress and HMGB1/TLR4/NF-κB pathway
por: Zhang, Xiong, et al.
Publicado: (2022)

Rhein: A Review of Pharmacological Activities
por: Zhou, Yan-Xi, et al.
Publicado: (2015)

β-Casomorphin-7 Ameliorates Sepsis-Induced Acute Kidney Injury by Targeting NF-κB Pathway
por: Zhang, ZhiJie, et al.
Publicado: (2019)

Danaparoid sodium inhibits systemic inflammation and prevents endotoxin-induced acute lung injury in rats
por: Hagiwara, Satoshi, et al.
Publicado: (2008)

Anti-Inflammatory Pyranochalcone Derivative Attenuates LPS-Induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Pathway
por: Shi, Min, et al.
Publicado: (2017)

The Molecular Mechanism of Rhein in Diabetic Nephropathy
por: Zeng, Cong-Cong, et al.
Publicado: (2014)

Effect of endotoxin absorption by polymixin B hemoperfusion in dialysis-requiring acute kidney injury
por: Iwagami, M, et al.
Publicado: (2015)

Angiotensin (1-7) Attenuates Sepsis-Induced Acute Kidney Injury by Regulating the NF-κB Pathway
por: Zhu, Ying, et al.
Publicado: (2021)

Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation
por: Pooladanda, Venkatesh, et al.
Publicado: (2019)

Rhein Induces Apoptosis in Human Breast Cancer Cells
por: Chang, Ching-Yao, et al.
Publicado: (2012)

Aldosterone-induced kidney injury is mediated by NFκB activation
por: Fukuda, Seiichi, et al.
Publicado: (2010)

Update on Pharmacological Activities, Security, and Pharmacokinetics of Rhein
por: Li, Gang-Min, et al.
Publicado: (2021)

Simvastatin Inhibits Endotoxin-Induced Apoptosis in Liver and Spleen Through Up-Regulation of Survivin/NF-κB/p65 Expression
por: Nežić, Lana, et al.
Publicado: (2019)

Protection of rhein on IgA nephropathy mediated by inhibition of fibronectin expression in rats
por: Sheng-Nan, Peng, et al.
Publicado: (2013)

Sappanone a prevents diabetic kidney disease by inhibiting kidney inflammation and fibrosis via the NF-κB signaling pathway
por: Wang, Zhe, et al.
Publicado: (2022)

Maresin 1 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting NOX4/ROS/NF-κB Pathway
por: Li, Jiameng, et al.
Publicado: (2021)

Melittin Ameliorates Endotoxin-Induced Acute Kidney Injury by Inhibiting Inflammation, Oxidative Stress, and Cell Death in Mice
por: Kim, Jung-Yeon, et al.
Publicado: (2021)

Gut derived-endotoxin contributes to inflammation in severe ischemic acute kidney injury
por: Li, Jiangtao, et al.
Publicado: (2019)

Pharmacokinetics and Pharmacodynamics of the Combination of Rhein and Curcumin in the Treatment of Chronic Kidney Disease in Rats
por: He, Xiaoying, et al.
Publicado: (2020)

Protective effect of hydroxysafflor yellow A against acute kidney injury via the TLR4/NF-κB signaling pathway
por: Bai, Juan, et al.
Publicado: (2018)

Cepabiflas B and C as Novel Anti-Inflammatory and Anti-Apoptotic Agents against Endotoxin-Induced Acute Kidney and Hepatic Injury in Mice: Impact on Bax/Bcl2 and Nrf2/NF-κB Signalling Pathways
por: Rizq, Akaber T., et al.
Publicado: (2023)

Rhein inhibits Chlamydia trachomatis infection by regulating pathogen-host cell
por: Yu, Xueying, et al.
Publicado: (2022)

Expression of TLR4-MyD88 and NF-κB in the Iris during Endotoxin-Induced Uveitis
por: Li, Shang, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_9782svulltlgu4vlmja3a6a8e2