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Incorporation of a GPI-anchored engineered cytokine as a molecular adjuvant enhances the immunogenicity of HIV VLPs

HIV vaccines should elicit immune responses at both the mucosal portals of entry to block transmission and systemic compartments to clear disseminated viruses. Co-delivery of mucosal adjuvants has been shown to be essential to induce effective mucosal immunity by non-replicating vaccines. A novel cy...

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Detalles Bibliográficos
Autores principales: Feng, Hao, Zhang, Han, Deng, Jiusheng, Wang, Li, He, Yuan, Wang, Shelly, Seyedtabaei, Roheila, Wang, Qing, Liu, Laiting, Galipeau, Jacques, Compans, Richard W., Wang, Bao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493578/
https://www.ncbi.nlm.nih.gov/pubmed/26150163
http://dx.doi.org/10.1038/srep11856