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Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling

Various strategies have been published enabling cardiomyocyte differentiation of human induced pluripotent stem (iPS) cells. However the complex nature of signaling pathways involved as well as line-to-line variability compromises the application of a particular protocol to robustly obtain cardiomyo...

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Detalles Bibliográficos
Autores principales: Kadari, Asifiqbal, Mekala, SubbaRao, Wagner, Nicole, Malan, Daniela, Köth, Jessica, Doll, Katharina, Stappert, Laura, Eckert, Daniela, Peitz, Michael, Matthes, Jan, Sasse, Philipp, Herzig, Stefan, Brüstle, Oliver, Ergün, Süleyman, Edenhofer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493626/
https://www.ncbi.nlm.nih.gov/pubmed/25392050
http://dx.doi.org/10.1007/s12015-014-9564-6