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Influence of rimonabant treatment on peripheral blood mononuclear cells; flow cytometry analysis and gene expression profiling

The cannabinoid receptor type 1 (CB1) antagonist rimonabant has been used as treatment for obesity. In addition, anti-proliferative effects on mitogen-activated leukocytes have been demonstrated in vitro. We have previously shown that rimonabant (SR141716A) induces cell death in ex vivo isolated mal...

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Detalles Bibliográficos
Autores principales: Almestrand, Stefan, Wang, Xiao, Jeppsson-Ahlberg, Åsa, Nordgren, Marcus, Flygare, Jenny, Christensson, Birger, Rössner, Stephan, Sander, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493638/
https://www.ncbi.nlm.nih.gov/pubmed/26157624
http://dx.doi.org/10.7717/peerj.1056