Cargando…

Active mechanistic target of rapamycin plays an ancillary rather than essential role in zebrafish CNS axon regeneration

The developmental decrease of the intrinsic regenerative ability of the mammalian central nervous system (CNS) is associated with reduced activity of mechanistic target of rapamycin (mTOR) in mature neurons such as retinal ganglion cells (RGCs). While mTOR activity is further decreased upon axonal i...

Descripción completa

Detalles Bibliográficos
Autores principales: Diekmann, Heike, Kalbhen, Pascal, Fischer, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493654/
https://www.ncbi.nlm.nih.gov/pubmed/26217179
http://dx.doi.org/10.3389/fncel.2015.00251