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The destructive effect of botulinum neurotoxins on the SNARE protein: SNAP-25 and synaptic membrane fusion
Synaptic exocytosis requires the assembly of syntaxin 1A and SNAP-25 on the plasma membrane and synaptobrevin 2 (VAMP2) on the vesicular membrane to bridge the two opposite membranes. It is believed that the three SNARE proteins assemble in steps along the dynamic assembly pathway. The C-terminus of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PeerJ Inc.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493708/ https://www.ncbi.nlm.nih.gov/pubmed/26157630 http://dx.doi.org/10.7717/peerj.1065 |